Therapie des Status epilepticus

Therapy of the Status Epilepticus. The status epilepticus is – second to stroke – the most common neurological emergency situation. The generalized convulsive status epilepticus (GCSE), the most severe and extreme expression of an epileptic seizure, is associated with a significant morbidity and one out of five patients will not survive. Only half of the patients have pre-existing epilepsy and the majority is acutely or remotely symptomatic, with brain trauma, cerebrovascular insults, brain infections and metabolic diseases as the most common causes. In patients with previous epilepsy a phase of increasing seizure activity (premonitory status) often heralds overt GCSE in which continuous epileptic activity prevails. Management of established GCSE prompts